(DOWNLOAD) "Potent Suppressive Effect of Green Tea Polyphenols on Tobacco-Induced Mutagenicity." by Phytomedicine: International Journal of Phytotherapy & Phytopharmacology " eBook PDF Kindle ePub Free

August 02, 2021

eBook details

Title: Potent Suppressive Effect of Green Tea Polyphenols on Tobacco-Induced Mutagenicity.
Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Release Date : January 01, 2005
Genre: Life Sciences,Books,Science & Nature,
Pages : * pages
Size : 194 KB

Description

Abstract Antimutagenic activity of green tea (Camellia sinensis) was studied using Salmonella typhimurium strains (TA 102) (Ames test). Aqueous tobacco extract was found to be mutagenic to S. typhimurium TA 102 at concentration of 50 mg/plate. Green tea polyphenols was found to inhibit the mutagenicity of tobacco in a concentration-dependent manner. Concentrations needed for 50% inhibition of mutagen-induced revertant formation was found to be 5 mg/plate. Green tea polyphenols was also found to inhibit the urinary mutagenicity in rats induced by tobacco extract. Moreover green tea polyphenols were found to inhibit in vitro nitrosation reaction produced by reaction sodium nitrite and methyl urea and further inhibition of mutagenicity indicating that green tea has dual action to bring out a reduction in the mutagenic and carcinogenic potential of tobacco.